Protein Chemical Modification on Endogenous Amino Acids

Selective chemical protein modification.

Chemical modification of proteins is an important tool for probing natural systems, creating therapeutic conjugates and generating novel protein constructs. Site-selective reactions require exquisite control over both chemo- and regioselectivity, under ambient, aqueous conditions. There are now various methods for achieving selective modification of both natural and unnatural amino acids--each ...

Effect of nitrogen fertilization on yield,protein and amino acids of irrigated mexipak wheat

Response of layers fed on diets dificient in protein and sulphur amino acids supplemented with lipid

Insights into Aurora-A Kinase Activation Using Unnatural Amino Acids Incorporated by Chemical Modification

Most protein kinases are regulated through activation loop phosphorylation, but the contributions of individual sites are largely unresolved due to insufficient control over sample phosphorylation. Aurora-A is a mitotic Ser/Thr protein kinase that has two regulatory phosphorylation sites on its activation loop, T287 and T288. While phosphorylation of T288 is known to activate the kinase, the fu...

The modification in quality of parsley (Petroselinum crispum) by selenium and amino acids .

This research was conducted with the purpose of appraising the effect of Selenium (Se) and/or amino acid fertilizers (AA) on improving growth, physiology, and biofortification of parsley grown under high EC condition. Plants were foliarly supplemented with four levels of Se (0, 25, 50, 100 mgl-1) and/or two concentrations of AA (0 and 0.2%) three times with a week interval. The significantly in...